TY - BOOK AU - Kahaly,George J. ED - SpringerLink (Online service) TI - 70 Years of Levothyroxine SN - 9783030632779 U1 - 616.4 23 PY - 2021/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Endocrinology KW - Pharmacology N1 - History Of Levothyroxine -- Pharmacokinetics Of Levothyroxine -- Pharmacodynamics Of Levothyroxine -- Levothyroxine In Pregnancy -- Levothyroxine In Children -- Levothyroxine In The Elderly -- Levothyroxine And Heart -- Levothyroxine And Bone -- Levothyroxine And Cancer -- Potential Adverse Reactions Of Levothyroxine; Open Access N2 - This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals UR - https://doi.org/10.1007/978-3-030-63277-9 ER -